(a) Serum LDH activity comparison: pre-treatment and one month post treatment in 46 dogs. The enzyme activity was measured with an automated biochemical analyser on the day of treatment and four weeks later. The analyses showed a statistically significant increase in the serum LDH activity one month after treatment (p = 0.012). BT, before treatment; 1 M AT, one month after treatment; * p < 0.05. (b) Serum LDH activity comparison: pre-treatment, one month post treatment and six months post treatment in 18 dogs. The enzyme activity was measured on the day of treatment, four weeks later and at the end of the observation period using an automated biochemical analyser. The analyses showed no statistically remarkable changes in the serum LDH activity (p > 0.999 for all comparisons). BT, before treatment; 1 M AT, one month after treatment; 6 M AT, six months after treatment; ns, not significant.