Figure 8.

Effects of MPOBA treatment on TP53, BCL-2, BAX, E-cadherin, N-cadherin, SNAIL, EGFR, SLUG, and TWIST mRNA expression in REM134 cells (A–I). Cells were treated with different concentrations of MPOBA for 48 h. The relative abundances of mRNA were normalized by GAPDH mRNA expression. The data were expressed as the mean ± SD values of four independent experiments. Differences among groups were analyzed using a Kruskal–Wallis test followed by Dunn’s multiple comparisons post hoc tests (* p < 0.05, ** p < 0.01 vs. untreated control).