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. 2024 Jan 31;16(3):600. doi: 10.3390/cancers16030600

Table 2.

Conditioning regimens in haploidentical haematopoietic stem cell transplantation with post-transplant cyclophosphamide at our centre.

MAC –9 –8 –7 –6 –5 –4 –3 –2 –1 0
TBI-based regimen
TBI 9.9–12 Gy
fludarabine 30 mg/m2/day
Non-TBI regimen
fludarabine 30 mg/m2/day
melphalan 90 mg/m2/day
fludarabine 30 mg/m2/day
targeted busulfan
(total AUC 80–100 mg × h/L)
RIC
fludarabine 30 mg/m2/day
melphalan 70 mg/m2/day
fludarabine 30 mg/m2/day
cyclophosphamide
14.5 mg/kg/day
TBI 2 Gy

MAC, myeloablative conditioning; TBI, total body irradiation; AUC, area under the concentration-time curve; RIC, reduced intensity conditioning; ↓, date of administration or irradiation.