Table 1.
Skin biomechanical properties (R0 and R2 average value ± SD) before and after treatment with 2.5%w/w AAO or Placebo.
Visit Day   Skin Parameter |
Baseline (D0) Mean ± SD |
Day 14 (D14) Mean ± SD |
∆% vs. D0 | Day 28 (D28) Mean ± SD |
∆% vs. D0 | |
|---|---|---|---|---|---|---|
| 2.5%w/w AAO | Skin pliability/firmness (R0) | 0.355 ± 0.024 mm | 0.322 ± 0.014 mm | −9.0% *** $$$ | 0.308 ± 0.028 mm | −13.0% *** $$$ |
| Gross elasticity (R2) | 0.602 ± 0.066% | 0.676 ± 0.052% | 14.0% *** $ | 0.759 ± 0.071% | 28.0% *** $$$ | |
| Placebo | Skin pliability/firmness (R0) | 0.308 ± 0.047 mm | 0.342 ± 0.037 mm | 8.0% | 0.342 ± 0.037 mm | 12.0% |
| Gross elasticity (R2) | 0.507 ± 0.044% | 0.521 ± 0.041% | 3.0% | 0.526 ± 0.038% | 4.0% |
t-test vs. D0 *** p < 0.001; ANOVA vs. Placebo $ p < 0.05, $$$ p < 0.001.