Table 3.
Percentage of positive-HRCT patients at t2 in the populations identified according to the trend in DLCO and FVC from t0 to t1.
| Trend in DLCO from t0 to t1 | Pts with Negative t2 HRCT | Pts with Positive t2 HRCT | Odds Ratio (Confidence Limits) | p-Value |
|---|---|---|---|---|
| DLCO ≥ 80% at t0 and t1 | 152 (94.4%) | 9 (5.6%) | Ref | |
| DLCO ≥ 80% at t0 and <80% at t1 | 46 (9.7%) | 1 (2.2%) | 0.37 (0.05–2.98) | 0.3479 |
| DLCO < 80% at t0 and ≥80% at t1 | 33 (86.6%) | 5 (13.3%) | 2.56 (0.81–8.13) | 0.1112 |
| DLCO < 80% at t0 and at t1 | 197 (86.6%) | 31 (13.3%) | 2.66 (1.23–5.75) | 0.0130 |
| Trend in FVC from t0 to t1 | Pts with Negative t2 HRCT | Pts with Positive t2 HRCT | Odds Ratio (Confidence Limits) | p-Value |
| FVC ≥ 80% at t0 and t1 | 380 (91.0%) | 35 (8.9%) | Ref | |
| FVC ≥ 80% at t0 and <80% at t1 | 12 (75.5%) | 4 (25.5%) | 3.62 (1.11–11.82) | 0.0331 |
| FVC < 80% at t0 and ≥80% at t1 | 10 (91.0%) | 1 (8.9%) | 1.09 (0.14–8.73) | 0.9384 |
| FVC < 80% at t0 and at t1 | 26 (81.0%) | 6 (18.9%) | 2.51 (0.97–6.50) | 0.0588 |