Figure 3.

Wound healing assay of melanoma cell lines treated with antiretroviral drugs. The time lapse of the wound healing assay confirms the inhibition of melanoma cell mobility following treatment with lamivudine (1 µM), doravirine (5 µM), or cabotegravir (3 µM) (abbreviated as LAMI, DORA, and CABO, respectively; CTR, untreated cells). Dacarbazine (DTIC), a medication commonly used in the treatment of melanoma, was employed for comparison. Images were captured using an inverted microscope (Axio Vert A1, Zeiss, Oberkochen, Germany), and quantitative analysis was performed using ImageJ computing software (Version: 2.14.0/1.54f. NIH Image, Bethesda, MD, USA). The statistical significance is reported in the Results section.