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. 2024 Feb 2;25(3):1826. doi: 10.3390/ijms25031826

Table 3.

Short QT syndrome subtypes [86,87,88,89].

SQTS Subtype Gene Channel Function Mechanism
SQTS1 KCNH2 α-subunit IKr Gain-of-function
SQTS 2 KCNH2 α-subunit IKs Gain-of-function
SQTS 3 KCNJ2 α-subunit IK1 Gain-of-function
SQTS 4 CACNA1C α-subunit ICaL Loss-of-function
SQTS 5 CACNB2 β2-subunit ICaL Loss-of-function
SQTS 6 CACNA2D1 Δ1-subunit ICaL Loss-of-function
SQTS 7 SCN5A α-subunit INa Loss-of-function
SQTS 8 SLC4A3 AE3 anion exchanger Loss-of-function

SQTS—short QT syndrome.