Figure 7.

PTCy with BBG does not alter proportions of liver human leukocytes or immune cell subsets compared to PTCy in GVL immunity at endpoint. (a–f) Liver suspensions from treated mice at endpoint (Figure 5) were examined by flow cytometry to determine the proportions of (a) human (h) CD45⁺ leukocytes, (b) hCD3⁺ T cells, (c) hCD4⁺ or hCD8⁺ T cells, (e) hCD4⁺hCD25⁺hCD127^lo regulatory T cell (hTreg), or (f) hCD39⁺ Tregs. (d) The ratio of hCD4⁺ to hCD8⁺ T cells was calculated from (c). (a–f) Data are presented as mean ± SEM. Symbols represent individual mice (n = 8, GVL; n = 9, GVL + PTCy + BBG).