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. 2024 Jan 27;25(3):1584. doi: 10.3390/ijms25031584

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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GO enrichment and Reactome pathway analysis of the significantly altered total proteome in AD. Gene Ontology enrichment analysis was performed for the significantly different total proteome between Controls and ADs, and the Top 10 biological processes (A) or molecular function (B) terms identified. Reactome pathway analysis (C) was also carried out. The terms with lowest p-value and higher number of genes associated were considered the most representative/relevant. Abbreviations: activ, activity; apopt, apoptosis; bind, binding; constitut; constitutive; cyst, cysteine; depend, dependent; downregul, downregulation; endopept, endopeptidase; heptapep, heptapeptide; independ, independent; memb, membrane; phospho, phosphorylation; posit, positive; recept, receptor; regul, regulation; resp, response; ser, serine; signal, signaling; surf, surface; thr, threonine; transcript, transcriptional regulation; transd, transduction; transmemb, transmembrane; transp; transporter; tyr, tyrosine.