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. 2024 Jan 25;29(3):597. doi: 10.3390/molecules29030597

Figure 4.

Figure 4

Binding modes of HAT constituents and VEGFR2 inhibitors to VEGFR2 kinase domain. Docking analysis was performed to investigate the structural interactions between VEGFR2 kinase domain and various compounds: (A) lupeol, (B) β-sitosterol, (C) sorafenib, and (D) sunitinib. HAT—hexane fraction of Adenophora triphylla var. japonica root extract; VEGFR2—vascular endothelial growth factor receptor 2.