Table 1.

Docking of β-sitosterol, lupeol, sorafenib, and sunitinib to VEGFR2 ¹ kinase domain.

Compound	Binding Residues in Kinase Domain	Binding ΔG
Lupeol	ALA866, VAL848, LEU840, LEU1035	−8.5
β-sitosterol	ALA866, VAL848, LEU840, LEU1035, CYS1045	−7.9
Sorafenib	ALA866, VAL848, LEU840, LEU1035, LYS868, ASP1046, CYS919, PHE1047	−8.0
Sunitinib	ALA866, VAL848, LEU840, ALA881, GLU885, LEU882, LYS868, GLY846, PHE918	−7.2

¹ Vascular endothelial growth factor receptor 2.