Table 1.
BA | BB | BH | Kruskal–Wallis Test | A | B | C | |
---|---|---|---|---|---|---|---|
(N = 67) | tp1 (N = 67) | tp1 (N = 77) | |||||
Mean/No. (SD) | Mean/No. (SD) | Mean (SD) | Corrected p Value | ||||
Age at tp1, years | 49.1 (8.3) | 50.2 (8.8) | 47.0 (8) | 0.45 | 0.51 | 0.02 * | 0.09 |
Education, years | 12.3 (3.8) | 11.9 (3.9) | 13 (3.2) | 0.08 | 0.61 | 0.03 * | 0.11 |
PHQ-9 | 3.9 (3.7) | 4.7 (4.1) | 2.9 (2.9) | 0.02 * | 0.91 | <0.01 * | 0.12 |
HADS-A | 3.6 (3.8) | 5 (4.4) | 3.9 (3.6) | 0.06 | 0.04 * | 0.12 | 0.43 |
Intracranial volume, milliliter | 1261.5 (100.7) | 1261.7 (97.8) | 1269.8 (95.4) | 0.76 | 0.98 | 0.48 | 0.60 |
days after complete chemotherapy | 223 (142.9) | ||||||
Breast cancer stage | |||||||
0 | 0 | 19 | |||||
I | 13 | 19 | |||||
II | 37 | 21 | |||||
III | 13 | 6 | |||||
IV | 4 | 2 |
Abbreviations: BA, postchemotherapy patients; BB, prechemotherapy patients; BH, healthy controls; tp1, time point 1; PHQ-9, Patient Health Questionnaire; HADS-A, Hospital Anxiety and Depression Scale–Anxiety. A = comparison between breast cancer patients before and after chemotherapy at time point 1 (BA; BB); B = comparison between breast cancer patients before chemotherapy and healthy controls at time point 1 (BB; BH); C = comparison between breast cancer patients after chemotherapy and healthy controls at time point 1 (BA; BH). Asterisks indicate significant differences (p < 0.05).