Table 2.

Clinical characteristic, laboratory, and neuroimaging findings of patients presenting with paraneoplastic neurological syndromes. Evaluation by use of the 2004 Paraneoplastic Neurological Syndrome Classification and the revised 2021 PNS-Care Diagnostic criteria [3,5].

Patient	Sex	Age	Syndrome	Antibody	Tumor	CSF Analysis	MRI Brain	2004 Score	PNS Score
1	F	50	Myasthenia gravis	AchR, Ti	Thymoma	N/A	Normal	N/A	N/A
2	F	56	Limbic encephalitis	Ma2	Papillary thyroid carcinoma	normal	Normal	Definite	7
3	M	87	Limbic encephalitis	ΙgLON5	Adenocarcinoma of prostate	normal	Small vessel disease	Definite	3
4	F	64	LEMS	P/Q-VGCC	Small-cell lung carcinoma	N/A	Normal	Definite	9
5	F	70	Myasthenia gravis	AchR	Thymoma	N/A	Normal	N/A	N/A
6	M	80	LEMS, Limbic encephalitis	Hu, P/Q-VGCC	Small cell lung carcinoma	Increased total protein level	T2/FLAIR hyperintensity in left mesial temporal lobe	Definite	10
7	F	85	Cerebellar Ataxia	Yo	Gastric adenocarcinoma	Increased total nucleated cell count & elevated total protein level	Greater degree of iron deposition in the posterior-lateral part of the lenticular nuclei and cerebellar atrophy	Definite	6
8	M	77	LEMS	Hu, P/Q-VGCC	Non- small cell lung carcinoma	N/A	Normal	Definite	10
9	M	78	Peripheral neuropathy	Hu	Small-cell lung carcinoma	Elevated total protein level	Normal	Definite	10
10	M	27	Limbic encephalitis	GAD65	Lymphohyperpla-stic disorder	Increased total nucleated cell count	Normal	Definite	3
11	F	60	Myasthenia gravis	AchR	Thymoma	N/A	Normal	N/A	N/A
12	F	50	Myasthenia gravis	AchR	Thymoma	N/A	Normal	N/A	N/A
13	M	50	Cerebellar Ataxia	Yo	Papillary thyroid carcinoma	Normal	Cerebellar atrophy	Definite	6

Abbreviations: M = male; F = female; AchR = muscle-type acetylcholine receptor binding antibodies; Ti = titin; GAD = glutamic acid decarboxylase; P/Q-VGCC = P/Q type voltage-gated calcium channel (VGCC) antibodies, LEMS = Lambert–Eaton myasthenic syndrome; N/A = not applicable.