Figure 3.

Influence of sterile fecal filtrates from donors on patients’ cells. Cells were stimulated in presence of GM-CSF and IL-2 for two days. Each metric is shown in both pairwise (dotted lines) and median-wise plots to illustrate the intra-individual dynamics of the parameter and the global dynamics over the study group. (a) IL-4 production in culture medium; (b) IL-10 production in culture medium; (c) presence of CD4⁺ T cells among the population survived after two days of ex vivo activation; (d) level of CD4⁺CD25⁺CD127⁺ cells capable of producing effector cytokines. **—designate significance level p < 0.001.