Figure 7.

Memory phenotypes of CD25⁺CD127⁺ T cells in ex vivo cultured conditions under stimulation with donor-derived stool filtrate. Plots description: (a) percent of activated T cells with phenotype of Central Memory cells (CD45RA⁻CD45RO⁺CCR7⁺); (b) Percent of cells with phenotype of TEMRA-Cells’ + 5; (c) Subset of cells with phenotype of Effector Memory cells; (d) Relative content of memory cell phenotypes in culture medium. Auto 0, Auto 1, and Auto 3 correspond to patient’s sterile stool filtrate derived before therapy, and 1, and 3 months in the following period. **—designate significance level p < 0.001, *—designate significance level p < 0.01.