Table 2.
Results.
| Overall Population | |||||||
|---|---|---|---|---|---|---|---|
| Baseline | Week 6 | Week 16 | Week 32 | Week 52 | Week 68 | Week 84 | |
| IGA-CNPG score (mean ± SD) | 3.7 ± 0.5 | 1.4 ± 1.1 | 0.6 ± 0.9 | 0.3 ± 0.5 | 0.5 ± 0.8 | 0.0 ± 0.0 | 0.0 ± 0.0 |
| itch-NRS score (mean ± SD) | 8.7 ± 1.7 | 1.6 ± 2.6 | 1.1 ± 1.6 | 2.1 ± 2.9 | 2 ± 3.1 | 0.0 ± 0.0 | 0.7 ± 1.1 |
| sleep-NRS (mean ± SD) | 5.8 ± 2.5 | 1.0 ± 2.2 | 0.1 ± 0.2 | 0.7 ± 1.4 | 1.0 ± 1.5 | 0.0 ± 0.0 | 0.0 ± 0.0 |
| DLQI score (mean ± SD) | 11.3 ± 5 | 1.5 ± 1.9 | 1.5 ± 2.6 | 2.7 ± 3.4 | 2.7 ± 4.1 | 0.5 ± 0.6 | 0.0 ± 0.0 |
| N.(%) patients reaching IGA-CNPG 0/1 | 72.7% | 76.9% | 100% | 83% | 100% | 100% | |
| N.(%) patients reaching ≥4-point amelioration DLQI | 82% | 92% | 100% | 83% | 75% | 67% | |
| N.(%) patients reaching ≥4-point amelioration itch—NRS | 91% | 100% | 78% | 83% | 100% | 100% | |
| N.(%) patients reaching ≥4-point amelioration sleep—NRS | 82% | 85% | 67% | 50% | 100% | 100% | |