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. 2024 Jan 24;29(3):572. doi: 10.3390/molecules29030572

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Selectivity evaluation. Ten lots of naive plasma samples (five females and five males) were used for selectivity evaluation at HQC and LLOQ levels. F1 to F5 stand for female 1 to female 5 plasma samples, and M1 to M5 stand for male 1 to male 5 plasma samples. The results indicated that 9/10 of individual test samples met the acceptance criteria, except that the bias % of female 3 (F3) at the LLOQ level was slightly beyond −25.0%. The dotted lines and dashed lines shown in (A) represent ±20% and ±25% ranges for the HQC and LLOQ, respectively. The dotted line and dashed lines shown in (B) represent 20% and 25% CV limits for the HQC and LLOQ, respectively.