Table 1.

Search strategy for Ovid Medline.

Search #	Search Term(s) and Combinations
1	(probiotic * or prebiotic * or synbiotic *): ti, ab, kw
2	(infant * or neonat * or newborn * or p?ediatric or child *): ti, ab, kw
3	(‘Erythrocyte sedimentation rate’ or ESR or interleukin * or IL or ‘tumo?r necrosis factor’ or TNF or cytokine * or Orosomucoid or ORM or ‘alpha 1 acid glycoprotein’ or AGP or CRP or ‘C reaction protein’ or GlycA or ‘systemic inflammation’): ti, ab, kw
4	(Randomi?ed controlled trial): ti, ab, kw
5	(Review or protocol): ti, ab, kw
6	1 AND 2 AND 3 AND 4 NOT 5

* wildcard representing one or more characters in the search.