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. 2024 Feb 2;13(3):442. doi: 10.3390/plants13030442

Figure 5.

Figure 5

M. orbicularis enhance cisplatin-induced cytotoxicity in A549 lung cancer cells. (A) Cell viability of A549 cells treated with the indicated concentrations of cisplatin was measured using MTT assay. Data are displayed as % cell viability relative to control (ctr) cells. * p < 0.05, *** p < 0.001, and **** p < 0.0001 (B) A549 cells were treated with fruit extracts of M. orbicularis (100 μg/mL) alone or combined with 5 μg/mL cisplatin (Cis) for 48 h, and then assayed for cell viability using MTT assay. Bar graphs represent % cell viability relative to control (ctr) cells. Data are presented as the mean ± SEM of three independent experiments (n = 3). Significant difference from control: **** p < 0.0001; significant difference from cisplatin treatment alone: #### denotes p < 0.0001; and significant difference from M. orbicularis alone: ‡ denotes p < 0.05. M. orbicularis F. denotes M. orbicularis fruits extracts.