TABLE 1.
Sequence accession numbers and features of UHB gene family members
| Accession number and gene name (reference) | Isolate of origina | Gene feature(s)b |
|---|---|---|
| L13924ospE (14) | N40 | First gene of the ospEF operon in B. burgdorferi isolate N40 |
| L13925ospF (14) | N40 | Second gene of the ospEF operon in isolate N40 |
| L78248ospEi (20) | B31 | 91% nt identity with N40 ospE but not 3′ flanked by ospF |
| L78250ospEi (20) | N40CH | 87% nt identity with N40 ospE, not 3′ flanked by a conserved ospF |
| U44912erpA (25) | B31T | Flanked 3′ by erpB in some isolates, 85% nt identity to ospE |
| U78764erpA2 | B31T | Identical in sequence to erpA but carried on a different cp32 in isolate B31 |
| U44912erpB (25) | B31T | Resides 3′ of erpA in some isolates, 36% nt identity to ospF |
| U44914erpC (25) | B31T | Flanked 3′ by erpD in some isolates, 88% nt identity to ospE |
| U44914erpD (25) | B31T | Resides 3′ of erpC in some isolates, 38% nt identity to ospF |
| U72996erpI (6) | B31T | Flanked 3′ by erpJ, 100% nt identity to erpA |
| U72997erpK (6) | B31T | Peripheral member of the UHB gene family exhibiting 54 and 68% nt identity with ospE and ospF, respectively |
| U72996erpJ (6) | B31T | Resides 3′ of erpI in isolate B31T, 100% nt identity to erpB |
| L78249ospEi (20) | 297CH | 86% nt identity with N40 ospE, not 3′ flanked by a conserved ospF |
| X82409pG (27) | ZS7 | Immediately upstream from the bapA (bapA is homologous to eppA [7]) |
| X82409bapA (27) | ZS7 | Downstream from pG, 80% amino acid similarity with eppA, not 5′ flanked by a UHB element |
| L32797p21 (26) | N40 | 86 and 84% nt identity to N40 ospE and B31 ospEi, respectively |
| U18292bbk2.10 (1) | 297 | 77% nt identity to ZS7 pG, 3′ flanked by bapA |
| U19754ospF (1) | 297 | 92 and 98% nt identity to N40 ospF and N40CH ospFi, respectively |
| L78245ospFi (20) | 297CH | 100% identity with N40CH ospFi, 5′ flanked by a UHB element, not preceded by ospE |
| L78251ospFi (20) | N40CH | 91% nt identity with N40 ospF, 5′ flanked by a UHB element, not preceded by ospE |
| L79960ospEF (20) | CA12 | Full-length ospEF operon, ospE and ospF exhibit 79 and 84% nt identity to N40 ospE and ospF, respectively |
| U30617bbk2.11 (1) | 297 | ospF variant |
a
All isolates are B. burgdorferi.
b
All genes or operons, unless otherwise indicated, are flanked at their 5′ ends by a highly conserved UHB element.