Table 4.
IgG GMCs for all antigens at Day 1 and Day 30.
| Group 1 (VVV) | Group 2 (HHV) | |||||||
|---|---|---|---|---|---|---|---|---|
| (N = 85) |
(N = 82) |
|||||||
| Endpoint | Timepoint | n | Observed Response | 95% CI | n | Observed Response | 95% CI | |
| Hib-PRP | GMC | Day 1 | 79 | 1.25 | (0.92, 1.70) | 81 | 0.11 | (0.10, 0.13) |
| Day 30 | 73 | 5.85 | (4.28, 8.00) | 76 | 5.12 | (3.88, 6.76) | ||
| HBsAg | GMC | Day 1 | 69 | 30.88 | (21.55, 44.23) | 73 | 32.38 | (21.21, 49.44) |
| Day 30 | 56 | 1111.50 | (784.67, 1574.46) | 69 | 470.60 | (292.00, 758.43) | ||
| Diphtheria toxoid | GMC | Day 1 | 73 | 0.08 | (0.06, 0.11) | 79 | 0.08 | (0.07, 0.10) |
| Day 30 | 69 | 3.24 | (2.69, 3.89) | 74 | 1.93 | (1.55, 2.39) | ||
| Tetanus toxoid | GMC | Day 1 | 73 | 0.17 | (0.14, 0.23) | 79 | 0.14 | (0.12, 0.17) |
| Day 30 | 69 | 7.73 | (5.88, 10.16) | 74 | 3.92 | (3.07, 4.99) | ||
| Pertussis – PT | GMC | Day 1 | 73 | 6.91 | (5.35, 8.93) | 79 | 7.15 | (5.86, 8.72) |
| Day 30 | 69 | 172.27 | (138.99, 213.53) | 74 | 59.41 | (48.58, 72.67) | ||
| Pertussis – FHA | GMC | Day 1 | 73 | 8.39 | (6.70, 10.49) | 79 | 29.52 | (24.90, 35.00) |
| Day 30 | 69 | 99.01 | (80.89, 121.20) | 74 | 147.03 | (124.94, 173.02) | ||
| Pertussis – PRN | GMC | Day 1 | 73 | 2.68 | (2.08, 3.45) | 79 | 1.39 | (1.20, 1.61) |
| Day 30 | 69 | 115.88 | (84.02, 159.83) | 74 | 3.21 | (2.49, 4.14) | ||
| Pertussis – FIM 2/3 | GMC | Day 1 | 73 | 18.01 | (13.47, 24.06) | 79 | 1.21 | (1.08, 1.37) |
| Day 30 | 69 | 337.60 | (250.90, 454.27) | 74 | 13.50 | (10.75, 16.96) | ||
| Poliovirus 1 | GMC | Day 1 | 62 | 38.94 | (24.12, 62.86) | 78 | 31.86 | (21.29, 47.68) |
| Day 30 | 66 | 2135.80 | (1448.73, 3148.73) | 69 | 1569.33 | (958.73, 2568.81) | ||
| Poliovirus 2 | GMC | Day 1 | 62 | 57.90 | (37.28, 89.92) | 78 | 53.12 | (33.76, 83.60) |
| Day 30 | 66 | 3020.62 | (2162.92, 4218.44) | 69 | 3470.29 | (2441.36, 4932.86) | ||
| Poliovirus 3 | GMC | Day 1 | 62 | 30.28 | (18.87, 48.57) | 78 | 33.78 | (23.10, 49.39) |
| Day 30 | 66 | 1161.50 | (687.73, 1961.64) | 69 | 2554.44 | (1704.39, 3828.46) | ||
N, number of participants allocated and vaccinated; n, number of participants contributing to the analysis.