Table 4.
Association between serum iron and type 2 diabetes (stratified by magnesium levels according to physiological status).
| N | Case (%) | OR (95%CI) | p | p interaction | ||
|---|---|---|---|---|---|---|
| Age, years | Magnesium, µg/dL | |||||
| ≤60 | ≤2673.2 | 645 | 169 (26.2) | 1.34 (0.92, 1.94) | 0.128 | 0.201 |
| >2673.2 | 712 | 64 (9.0) | 0.91 (0.54, 1.53) | 0.727 | ||
| >60 | ≤2673.2 | 454 | 232 (51.1) | 1.48 (1.02, 2.16) | 0.039 | 0.332 |
| >2673.2 | 387 | 37 (9.6) | 0.80 (0.38, 1.70) | 0.567 | ||
| Gender | ||||||
| Men | ≤2673.2 | 345 | 152 (44.1) | 1.92 (1.20, 3.07) | 0.006 | 0.073 |
| >2673.2 | 427 | 48 (11.2) | 0.95 (0.51, 1.78) | 0.870 | ||
| Women | ≤2673.2 | 754 | 249 (33.0) | 1.16 (0.84, 1.61) | 0.358 | 0.383 |
| >2673.2 | 672 | 53 (7.9) | 0.88 (0.49, 1.57) | 0.661 | ||
| BMI, kg/m2 | ||||||
| ≤24 | ≤2673.2 | 488 | 157 (32.2) | 1.35 (0.90, 2.02) | 0.145 | 0.989 |
| >2673.2 | 514 | 39 (7.6) | 1.26 (0.65, 2.46) | 0.491 | ||
| >24 | ≤2673.2 | 611 | 244 (40.0) | 1.49 (1.05, 2.10) | 0.024 | 0.017 |
| >2673.2 | 585 | 62 (10.6) | 0.70 (0.41, 1.21) | 0.198 |
Odds ratios (95% confidence intervals) and p values were obtained from the logistic regression model adjusted for age, gender, body mass index, total cholesterol, and triglycerides. Serum iron was included in the analysis as a binary variable according to the median, with the lower group serving as the reference group. p-values for interaction were assessed using a likelihood ratio test to compare the models with and without interaction terms. BMI, body mass index; OR, odds ratio; CI, confidence interval.