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. 2024 Feb 9;19(2):e0289248. doi: 10.1371/journal.pone.0289248

Fig 1. Effects of the CRS, AGO, and DFX intervention on body weight and behavioral tests.

Fig 1

Depression-like behavior in mice induced by CRS. (a) Initial body weight of the mice. (b) Body weight of the mice after different treatments. (c) Weight gain of the mice. (d) Sucrose preference rate in mice. (e) Forced swimming rest time in mice. (f) The total distance of mice in the central region of the open field test. (g) Total time of mice in the central region in the open field test. (h) The total distance of mice in the open field test. *P<0.05; ** P<0.01; *** P<0.001; CRS, chronic restraint stress; AGO, agomelatine; DFX, deferasirox; ns, no significant difference. Data are expressed as the mean ± standard deviation and were analyzed by one-way ANOVA, followed by post hoc multiple comparisons (LSD method). n = 10.