Table 2.
Associations of antidepressant use patterns during pregnancy with birth outcomes
| Adjusted Relative Risk† (95% CI) | ||
|---|---|---|
| Continued use vs discontinued use | Continued use vs stopped and reinitiated | |
| Preterm birth | 1.86 (1.53, 2.27) | 1.66 (1.27, 2.18) |
| NICU admission | 1.76 (1.42, 2.19) | 1.85 (1.39, 2.46) |
Model is adjusted for maternal age (years), race/ethnicity (Asian, non-Hispanic Black, Hispanic, non-Hispanic White, other), education (high school graduate or less, some college, college graduate or more), Medicaid during pregnancy (Y/N), nulliparity (Y/N), alcohol use during pregnancy (Y/N), tobacco use during pregnancy (Y/N), other drug use during pregnancy (Y/N), and maximum Patient Health Questionnaire (PHQ-9) score during pregnancy
Note: NICU, neonatal intensive care unit. Additional adjustment for an interaction term between exposure category and Patient Health Questionnaire (PHQ-9) score was not significant at the α=0.1
0 level (not shown)