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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Pharmacotherapy. 2023 Mar 19;43(5):372–380. doi: 10.1002/phar.2790

Table 2.

Associations of antidepressant use patterns during pregnancy with birth outcomes

Adjusted Relative Risk (95% CI)
Continued use vs discontinued use Continued use vs stopped and reinitiated
Preterm birth 1.86 (1.53, 2.27) 1.66 (1.27, 2.18)
NICU admission 1.76 (1.42, 2.19) 1.85 (1.39, 2.46)

Model is adjusted for maternal age (years), race/ethnicity (Asian, non-Hispanic Black, Hispanic, non-Hispanic White, other), education (high school graduate or less, some college, college graduate or more), Medicaid during pregnancy (Y/N), nulliparity (Y/N), alcohol use during pregnancy (Y/N), tobacco use during pregnancy (Y/N), other drug use during pregnancy (Y/N), and maximum Patient Health Questionnaire (PHQ-9) score during pregnancy

Note: NICU, neonatal intensive care unit. Additional adjustment for an interaction term between exposure category and Patient Health Questionnaire (PHQ-9) score was not significant at the α=0.1

0 level (not shown)