Skip to main content
. Author manuscript; available in PMC: 2024 Jun 5.
Published in final edited form as: Nat Cardiovasc Res. 2023 Dec 5;2(12):1277–1290. doi: 10.1038/s44161-023-00388-7

Extended data Fig. 2 |. Hematopoietic Cpt1a deficiency reduces hematopoiesis.

Extended data Fig. 2 |

A, Quantification of blood leukocytes in Cpt1afl/fl controls and Vav1iCre+Cpt1Afl/fl mice on day 3 after MI (n=6 Cpt1Afl/fl, n=7 Vav1iCre+Cpt1Afl/fl, two-tailed Welch’s t test, three independent experiments). B, Bone marrow SLAM-LSK numbers and proliferation and leukocyte numbers in Cpt1afl/fl controls and Vav1iCre+Cpt1Afl/fl mice on day 3 after MI (n=6 Cpt1Afl/fl, n=8 Vav1iCre+Cpt1Afl/fl, two-tailed Welch’s t test, three independent experiments). Data are displayed as mean±SEM. C, Gene essentiality (Chronos) scores for CPT1A (red curve) and F13B (blue, a control gene expressed in hematopoietic cells).