Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jan 4;43(7):511–523. doi: 10.1038/s41388-023-02918-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — A The levels of immunosuppressive (IL-4, IL-10, and IL-13) and pro-inflammatory (IL-6, IL-1β, and TNF-α) cytokines detected at weeks 0, 3, and 7 during EOC progression in the same ID8 intraperitoneal inoculation model as shown in Fig. 1C. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001. B The representative density plots from flow cytometry analysis of peritoneal cells harvested by peritoneal lavage indicate the proportion of CD11b⁺F4/80⁺CD206⁺ cells in Lect2^−/− and Lect2^+/+ mice. C Accumulation of CD11b⁺F4/80⁺CD206⁺ cells in the malignant ascites of ID8^/Lect2^−/− and ID8/Lect2^+/+ mice. Peritoneal cells were harvested 5 weeks after ID8 inoculation and analyzed by flow cytometry. D The bar chart of CD206⁺ macrophage proportions with or without ID8 tumor challenge in Lect2^−/− and Lect2^+/+ mice. *P < 0.05 and **P < 0.01. E The representative density plots from flow cytometry analysis gated on the abundance of CD45⁺CD11b⁺Ly6C⁺Ly6G^- (M-MDSC) and CD45⁺CD11b⁺Ly6C^-Ly6G⁺ cells (PMN-MDSC) in ID8^/Lect2^−/− and ID8/Lect2^+/+ mice. F Quantification of the ascitic M-MDSC and PMN-MDSC in ID8/Lect2^−/− and ID8/Lect2^+/+ mice. **P < 0.01.