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. 2023 Oct 31;183(1):371–378. doi: 10.1007/s00431-023-05297-2

What is Known:

• Empirical and unselected use of midodrine hydrochloride has an unfavorable therapeutic effect on VVS in children. Serum uric acid (UA) is closely linked to cardiovascular events.

What is New:

• A low baseline serum UA level successfully predicts the therapeutic effectiveness of midodrine hydrochloride on VVS in children.