TABLE 3.
Multivariate Analysis of Factors Associated with OS
| Factor | HR | P | Adjusted HR | Adjusted P |
|---|---|---|---|---|
| PDA vs. SDA | 0.51 (0.29–0.9) | 0.018 | — | — |
| Resection after SIRT, yes vs. no | 0.17 (0.06–0.43) | <10−3 | 0.15 (0.06–0.4) | <10−3 |
| Sex, female vs. male | 0.86 (0.27–2.77) | 0.797 | — | — |
| Age, >65 y vs. ≤65 y | 1.13 (0.63–2) | 0.684 | — | — |
| Child Pugh score, A6 or B7 vs. A5 | 1.61 (0.84–3.1) | 0.151 | — | — |
| ECOG, 1 vs. 0 | 1.23 (0.69–2.19) | 0.471 | — | — |
| Cirrhosis, yes vs. no | 2.4 (0.94–6.12) | 0.059 | — | — |
| Multifocal vs. unifocal | 20.3 (1.13–3.65) | 0.016 | — | — |
| Bilobar vs. unilobar | 2.1 (1.17–3.76) | 0.011 | 2.33 (1.24–4.37) | 0.008 |
| PVT, yes vs. no | 1.88 (0.98–3.63) | 0.054 | — | — |
| Treatment line, subsequent vs. first | 1.09 (0.54–2.21) | 0.808 | — | — |
| Index lesion size, ≥10 cm vs. <10 cm | 0.99 (0.56–1.76) | 0.968 | — | — |
| AFP, ≥200 μg/L vs. <200 μg/L | 1.6 (0.91–2.83) | 0.098 | — | — |
| Tumor involvement, ≥50% vs. <50% | 0.95 (0.29–3.07) | 0.927 | — | — |
| TD, ≥205 Gy vs. <205 Gy | 0.42 (0.22–0.81) | 0.007 | — | — |
| PLD, ≥150 Gy vs. <150 Gy | 0.42 (0.23–0.75) | 0.002 | — | — |
ECOG = Eastern Cooperative Oncology Group; AFP = α-fetoprotein.
Data in parentheses are 95% CIs.