TABLE 3.

Univariate Analysis of the Predictive Value of PET/CT Features in Time-Dependent AUC and Hazard Ratios

	PFS		OS
Clinical and PET/CT feature	AUC	HR	AUC	HR
Known features
IPI	0.60 (0.54–0.66)	3.45 (1.09–8.66)	0.61 (0.53–0.69)	6.18 (1.47–17.44)
TMTV	0.67 (0.59–0.74)	12.03 (2.15–57.56)	0.67 (0.58–0.76)	18.16 (2.63–108.20)
Dmax	0.64 (0.58–0.70)	7.87 (2.04–18.87)	0.62 (0.53–0.70)	7.39 (1.43–18.38)
Dbulk	0.63 (0.55–0.69)	5.59 (1.56–14.15)	0.62 (0.53–0.70)	6.96 (1.25–18.24)
New features
SpreadSpleen	0.64 (0.57–0.70)	5.85 (1.63–15.16)	0.63 (0.54–0.70)	9.87 (1.66–31.45)
Dspleen	0.66 (0.59–0.74)	17.49 (3.62–60.47)	0.64 (0.55–0.72)	18.18 (2.30–54.66)
sDspleen	0.66 (0.60–0.72)	53.28 (10.01–181.01)	0.65 (0.57–0.73)	32.51 (2.18–348.53)

HR = hazard ratio.

Data are mean with 95% CI.