. 2024 Feb 10;73(2):40. doi: 10.1007/s00262-023-03582-5

Table 2.

Number of CD8⁺ T cells, PD-L1⁺ cells, and PD-L1⁺CD8⁺ double-positive T cells in the spleen and tumor of each group (mean ± SD)

Group	Spleen			Tumor
Group	CD8⁺ T cells	PD-L1⁺ cells	PD-L1⁺CD8⁺ T cells	CD8⁺ T cells	PD-L1⁺ cells	PD-L1⁺ CD8⁺ T cells
C	23.67 ± 6.66	23.00 ± 5.00	18.00 ± 3 0.00	30.00 ± 6.24	31.00 ± 6.56	26.33 ± 5.69
wtT	19.33 ± 6.70^b	20.00 ± 3.46	18.67 ± 4.16	27.00 ± 6.06^b	28.67 ± 6.66	24.33 ± 6.03^c
shNT	20.33 ± 3.37^a	21.00 ± 6.00	17.00 ± 2.65^a	20.67 ± 3.37^a	28.00 ± 4.00	19.67 ± 2.89^a
shDT	32.00 ± 8.29^a	29.00 ± 2.65^b	26.33 ± 3.79^ab	35.67 ± 9.91^a	35.67 ± 4.51^b	33.33 ± 3.79^ab
oeNT	22.33 ± 4.51	21.67 ± 4.16^a	20.00 ± 2.65	26.67 ± 7.8	29.00 ± 3.61^a	23.00 ± 2.65
oeDT	30.33 ± 4.97	14.33 ± 2.52^abc	14.00 ± 2.65^bc	32.67 ± 8.85	18.00 ± 3.46^abc	16.33 ± 4.04^bd
wtT + PD-1 mAb	35.33 ± 5.51	31.67 ± 6.51	30.00 ± 5.00	38.33 ± 6.99	39.67 ± 5.69	36.33 ± 7.57
shDT + PD-1 mAb	39.33 ± 10.74	34.00 ± 7.21	31.00 ± 5.29	46.00 ± 5.45	55.00 ± 9.00^d	45.00 ± 6.56^e
oeDT + PD-1 mAb	36.33 ± 4.20^b	26.67 ± 4.16^c	24.00 ± 7.21^c	41.00 ± 3.56^b	34.67 ± 4.62^cd	33.00 ± 3.61^cde

The same superscript letter (e.g., a, b, c) indicates a significant difference between the groups (p < 0.05). Abbreviations: C: control; wtT: wild-type CD3⁺ T cells; shDT: CD3⁺ T cells with Drp1 knockdown; oeDT: CD3⁺ T cells with Drp1 overexpression; shNT and oeNT: negative control groups of T-shDrp1 and T-oeDrp1, respectively; PD-1 mAb: programmed cell death protein 1 monoclonal antibody; PBS: phosphate-buffered saline