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. 2024 Feb 10;14:3423. doi: 10.1038/s41598-024-54120-x

Table 1.

Demographics, salivary flow rate, and distribution of xerostomia.

Parameter Group 1 (n = 45) Group 2 (n = 338) Group 3 (n = 446) p-value Post-hoc
Mean ± SD or n (%) Mean ± SD or n (%) Mean ± SD or n (%)
Agea 19.67 ± 6.48 48.79 ± 8.22 71.31 ± 7.58  < 0.001 1 < 2, 1 < 3, 2 < 3
Sexb
Female 18 (40.0%) 249 (73.7%) 324 (72.6%)  < 0.001 Female: 1 < 2, 1 < 3
Male 27 (60.0%) 89 (26.3%) 122 (27.4%)
Salivary flow rate
UFRa 0.64 ± 0.39 0.42 ± 0.24 0.32 ± 0.20  < 0.001 1 > 3, 2 > 3, 1 > 2
SFRa 1.43 ± 0.84 1.39 ± 0.87 1.27 ± 0.86 0.113
Xerostomiab 5 (11.1%) 63 (18.6%) 131 (29.4%)  < 0.001 1 < 2, 1 < 3, 2 < 3
Systemic disease
Number of systemic diseasesa 0.07 ± 0.33 0.61 ± 0.92 1.34 ± 1.15  < 0.001 1 < 2, 1 < 3, 2 < 3
Number of medicationsa 0.22 ± 0.42 0.46 ± 0.85 0.99 ± 1.26  < 0.001 1 < 3, 2 < 3

Significant are in value [bold].

a Results were analyzed using ANOVA. b Results were obtained using χ2 test and repeated χ2 test between two age groups. Group 1 (1): 0–29 years, Group 2 (2): 30–59 years, Group 3 (3): 60–100 years.