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. 2024 Feb 10;22:107. doi: 10.1186/s12964-024-01494-0

Fig. 1.

Fig. 1

Pathophysiology of cervical cancer. Although genetic mutations and epigenetic alterations can give rise to the onset of CC, HPV infection is also considered a major leading cause for the progression of this gynecological malignancy. Circ-ATP8A2 and circSLC26A4 are key circRNAs, being involved in CC pathogenesis by up-regulating HOXA1 and EGFR mRNAs through sponging specific miRNAs. The figure has been created by https://www.BioRender.com