Table 3.
Statistics of ROI-based SA asymmetry index for the human and chimpanzee brain
| Surface area | Human | Chimpanzee | Species difference | |||
|---|---|---|---|---|---|---|
| ROIs | AI | P-value | AI | P-value | t-stats | P-value |
| Frontal | ||||||
| Superior frontal | −0.02 | −0.03* | 0.01 | 0.40 | −2.14 | 0.03* |
| Rostral middle frontal | −0.02 | −0.04* | −0.01 | −0.46 | −0.59 | 0.56 |
| Caudal middle frontal | 0.01 | 0.68 | 0.01 | 0.68 | 0.08 | 0.93 |
| Pars opercularis | 0.01 | 0.51 | 0.00 | 0.90 | 0.41 | 0.68 |
| Pars triangularis | 0.02 | 0.12 | −0.00 | −0.85 | 1.04 | 0.30 |
| Pars orbitalis | 0.01 | 0.32 | −0.02 | −0.45 | 1.17 | 0.24 |
| Lateral orbito frontal | 0.01 | 0.13 | 0.03 | 0.10 | −1.06 | 0.29 |
| Medial orbito frontal | −0.09 | −0.00** | 0.01 | 0.78 | −2.81 | 0.01* |
| Precentral | −0.01 | −0.06 | −0.01 | −0.15 | −0.58 | 0.56 |
| Paracentral | 0.01 | 0.36 | −0.02 | −0.02* | 1.72 | 0.09 |
| Frontal pole | −0.02 | −0.13 | 0.00 | 0.83 | −1.28 | 0.20 |
| Parietal | ||||||
| Superior parietal | −0.03 | −0.002* | 0.01 | 0.37 | −2.91 | 0.00* |
| Inferior parietal | −0.05 | −0.00** | −0.00 | −0.79 | −3.80 | 0.00** |
| Supramarginal | 0.10 | 0.00** | 0.01 | 0.10 | 5.47 | 0.00** |
| Postcentral | 0.03 | 0.00** | −0.00 | −0.68 | 3.25 | 0.00** |
| Precuneus | −0.01 | −0.16 | −0.01 | −0.51 | −0.30 | 0.76 |
| Temporal | ||||||
| Middle temporal | −0.00 | −0.58 | 0.01 | 0.39 | −1.03 | 0.30 |
| Inferior temporal | 0.04 | 0.00** | 0.01 | 0.31 | 1.86 | 0.06 |
| Superior temporal | 0.02 | 0.03* | 0.03 | 0.00** | −1.68 | 0.10 |
| Bankssts | −0.05 | −0.02* | −0.01 | −0.17 | −1.43 | 0.15 |
| Fusiform | −0.00 | −0.97 | 0.01 | 0.34 | −0.81 | 0.42 |
| Transverse temporal | 0.07 | 0.00** | 0.02 | 0.04* | 2.53 | 0.01* |
| Entorhinal | −0.02 | −0.23 | −0.06 | −0.13 | 0.83 | 0.41 |
| Temporal pole | 0.07 | 0.00** | 0.02 | 0.37 | 1.93 | 0.05 |
| Parahippocampal | −0.00 | −0.96 | −0.02 | −0.50 | 0.61 | 0.54 |
| Occipital | ||||||
| Lateral occipital | −0.01 | −0.24 | −0.02 | −0.08 | 0.53 | 0.60 |
| Lingual | −0.03 | −0.01* | −0.00 | −0.88 | −1.35 | 0.18 |
| Cuneus | −0.09 | −0.00** | 0.08 | 0.00** | −7.04 | 0.00** |
| Pericalcarine | −0.06 | −0.00** | 0.00 | 0.99 | −2.27 | 0.02* |
| Cingulate and insula | ||||||
| Caudal anterior cingulate | −0.09 | −0.003* | 0.05 | 0.02* | −3.69 | 0.00** |
| Isthmus cingulate | 0.07 | 0.00** | −0.00 | −0.99 | 2.16 | 0.03* |
| Posterior cingulate | −0.03 | −0.02* | 0.01 | 0.70 | −1.95 | 0.05 |
| Rostral anterior cingulate | 0.02 | 0.32 | 0.16 | 0.03* | −1.36 | 0.18 |
| Insula | −0.01 | 0.10 | 0.00 | 0.51 | −1.33 | 0.19 |
Note: *Denotes ROIs with significant asymmetry (i.e., P < 0.05 uncorrected for multiple comparisons), and **denotes ROIs with highly significant asymmetry that survived the Bonferroni correction (i.e., P < 0.05/34).