Table 4.
Statistics of ROI-based CT asymmetry index for the human and chimpanzee brain
| Cortical thickness | Human | Chimpanzee | Species difference | |||
|---|---|---|---|---|---|---|
| ROIs | AI | P-value | AI | P-value | t-stats | P-value |
| Frontal | ||||||
| Superior frontal | 0.02 | 0.00** | −0.00 | −0.94 | 4.75 | 0.00** |
| Rostral middle frontal | 0.03 | 0.00** | 0.02 | 0.01* | 0.95 | 0.34 |
| Caudal middle frontal | 0.00 | 0.34 | −0.01 | −0.45 | 1.20 | 0.23 |
| Pars opercularis | 0.00 | 0.38 | 0.00 | 0.87 | 0.38 | 0.70 |
| Pars triangularis | −0.00 | −0.61 | 0.01 | 0.31 | −1.16 | 0.25 |
| Pars orbitalis | −0.02 | −0.08 | −0.01 | −0.31 | −0.29 | 0.78 |
| Lateral orbito frontal | 0.01 | 0.16 | −0.01 | −0.11 | 2.15 | 0.03* |
| Medial orbito frontal | 0.00 | 0.93 | −0.01 | −0.41 | 0.72 | 0.47 |
| Precentral | 0.00 | 0.61 | −0.03 | −0.00** | 3.84 | 0.00** |
| Paracentral | −0.02 | −0.005* | −0.04 | −0.00** | 2.21 | 0.03* |
| Frontal pole | 0.02 | 0.07 | 0.00 | 0.99 | 1.10 | 0.27 |
| Parietal | ||||||
| Superior parietal | 0.01 | 0.14 | −0.00 | −0.42 | 1.58 | 0.12 |
| Inferior parietal | −0.01 | −0.02* | −0.00 | −0.65 | −0.94 | 0.35 |
| Supramarginal | 0.00 | 0.69 | 0.01 | 0.03* | −1.33 | 0.18 |
| Postcentral | 0.01 | 0.05 | −0.00 | −0.28 | 2.19 | 0.03* |
| Precuneus | −0.00 | −0.98 | 0.03 | 0.00** | −3.67 | 0.00** |
| Temporal | ||||||
| Middle temporal | −0.02 | −0.00** | 0.01 | 0.06 | −3.88 | 0.00** |
| Inferior temporal | −0.02 | −0.00** | −0.00 | −0.81 | −2.02 | 0.04* |
| Superior temporal | −0.02 | −0.002* | −0.00 | −0.64 | −1.67 | 0.10 |
| Bankssts | −0.03 | −0.00* | 0.00 | 0.83 | −2.09 | 0.04* |
| Fusiform | −0.01 | −0.03* | −0.01 | −0.26 | −0.26 | 0.79 |
| Transverse temporal | −0.01 | −0.55 | −0.03 | −0.01* | 1.83 | 0.07 |
| Entorhinal | −0.02 | −0.06 | −0.00 | −0.83 | −0.86 | 0.39 |
| Temporal pole | −0.00 | −0.75 | −0.01 | −0.71 | 0.16 | 0.88 |
| Parahippocampal | −0.02 | −0.01* | −0.04 | −0.00** | 1.28 | 0.20 |
| Occipital | ||||||
| Lateral occipital | −0.03 | −0.00** | −0.02 | −0.00** | −1.27 | 0.21 |
| Lingual | −0.04 | −0.00** | −0.01 | −0.16 | −3.26 | 0.00** |
| Cuneus | −0.03 | −0.00** | 0.00 | 0.97 | −3.63 | 0.00** |
| Pericalcarine | −0.04 | −0.00** | 0.01 | 0.38 | −3.70 | 0.00** |
| Cingulate and insula | ||||||
| Caudal anterior cingulate | 0.01 | 0.38 | 0.06 | 0.00** | −2.54 | 0.01* |
| Isthmus cingulate | −0.00 | −0.97 | −0.02 | −0.08 | 1.33 | 0.18 |
| Posterior cingulate | 0.01 | 0.11 | 0.00 | 0.62 | 0.68 | 0.50 |
| Rostral anterior cingulate | 0.06 | 0.00** | 0.05 | 0.01* | 0.53 | 0.60 |
| Insula | 0.00 | 0.49 | 0.02 | 0.00** | −2.52 | 0.01* |
Note: *Denotes ROIs with significant asymmetry (i.e., P < 0.05 uncorrected formultiple comparisons), and **denotes ROIs with highly significant asymmetry that survived the Bonferroni correction (i.e., P < 0.05/34).