Table 5.

In-silico ADME properties of reference molecule and 5g and 5h.

Sr No.	Parameters	Reference	5g	5h
1.	HB Donor	1	2	3
2.	HB Acceptor	2	13	14
3.	LogPo/w	3.496	0.072	−0.973
4.	logBBB	−0.487	−3.772	−3.716
5.	Metabolism	2	1	2
6.	% Human oral Absorption	92.674	15.211	8.391
7.	PSA	46.701	202.748	212.002
8.	Ro5 Violation	0	1	1
9.	Ro3 Violation	0	1	1
10.	Molecular Weight	206.284	462.387	427.342