Table 1.
Characteristics at baseline in transgender and cisgender people
| Transgender (n = 78) AFAB |
Cisgender (n = 57) Females |
Transgender (n = 47) AMAB |
Cisgender (n = 89) Males |
|
|---|---|---|---|---|
| Age [years] | 26.09 ± 7.42 | 27.66 ± 5.81 | 26.89 ± 8.72 | 24.89 ± 5.36 |
| Active smokers [%] | 36 (46.2%) | 20 (35%)* | 12 (25.5%) | 10 (11.25%)* |
| BMI [kg/m2] | 23.99 ± 6.67 | 22.62 ± 3.12 | 22.76 ± 4.11 | 23.67 ± 4.02 |
| Densitometric parameters | ||||
| z-score lumbar | − 0.27 ± 1.12 | − 0.20 ± 1.76 | − 0.99 ± 1.26 | − 0.08 ± 1.22*** |
| z-score femur | − 0.18 ± 1.08 | 0.04 ± 0.74 | − 0.66 ± 0.83 | 0.08 ± 0.81*** |
| z-score femur neck | − 0.32 ± 1.07 | − 0.07 ± 0.80 | − 0.71 ± 0.80 | 0.08 ± 0.93*** |
| Biochemical parameters | ||||
| 25-OHD [nmol/L] |
52.50 (36.15;66.25) |
80.00*** (38.00;112.00) |
52.38 (34.81;71.87) |
74.50*** (61.75;87.25) |
| Calcium [mg/dL] |
9.38 (9.10;9.70) |
9.60 (9.20;10.24) |
9.83 (9.73;10.00) |
9.74 (9.36;9.96) |
| Phosphate [mg/dL] |
3.50 (3.01;4.10) |
3.19 (2.88;3.38) |
3.30 (2.95;3.63) |
3.13 (2.76;3.61) |
| PTH [ng/L] |
38.00 (24.00;56.00) |
30.00 (22.00;47.50) |
32.90 (17.82;49.50) |
30.25 (20.75;52.00) |
Values are expressed as mean ± standard deviation or as median (interquartile range) or as count (percentages) as appropriate
The p values < 0.05 are shown in bold
AFAB assigned female at birth, AMAB assigned male at birth, BMI body mass index, 25-OHD 25-hydroxy vitamin D, PTH parathyroid hormone
*p < 0.05; **p < 0.01; ***p < 0.001