Table 1.
Changes in fat body mass densitometric parameters during 12-months Degarelix treatment
| Before Degarelix | After Degarelix | Percent variation | p | |
|---|---|---|---|---|
| BMI | 26.8 ± 4.3 | 27.7 ± 4.2 | 3.7 ± 4.8 | < .001 |
| TOT Fat (g)* | 18,957.4 (15,888.2; 26,588.8) | 23,002.9 (17,823.0; 27,649.3) | 10.0 (5.5; 22.3) | < .001 |
| Left Arm Fat (g) | 1236.4 ± 500.3 | 1393.2 ± 495.8 | 16.2 ± 22.1 | .005 |
| Right Arm Fat (g) | 1335.6 ± 529.3 | 1362.1 ± 509.2 | 5.0 ± 21.9 | .623 |
| Left Leg Fat (g) | 2843.2 ± 1243.5 | 3450.5 ± 1327.8 | 25.4 ± 20.4 | < .001 |
| Right Leg Fat (g) | 3028.9 ± 1327.5 | 3612.8 ± 1305.1 | 24.0 ± 20.5 | < .001 |
| Trunk Fat (g)* | 10,869.6 (8432.3–14,972.9) | 12,459.8 (8834.2—15,393.9) |
8.0 (2.5—20.9) |
< .001 |
| Head Fat (g) | 1083.6 ± 127.3 | 1045.3 ± 129.2 | -3.3 ± 8.3 | .036 |
| Android %Fat* | 32.5 (26.5–37.8) | 34.3 (29.2—40.1) | 6.6 (-5.2—13.0) | .012 |
| Gynoid %Fat | 25.5 ± 5.6 | 29.9 ± 4.9 | 19.2 ± 13.5 | < .001 |
| Android/Gynoid Ratio | 1.3 ± .2 | 1.1 ± .2 | − 8.9 ± 10.0 | < .001 |
| Trunk/Appendicular Fat ratio | 1.4 ± .3 | 1.3 ± .3 | − 3.9 ± 14.7 | .114 |
| VAT mass (g)* | 817.0 (697.0–1025.0) | 809.5 (668.3–1015.8) | 3.2 (− 2.6–19.1) | .125 |
| VAT Volume (cm3)* | 883.0 (753.0–1108.0) | 875.5 (722.8–1098.3) | 3.1 (− 2.6–19.1) | .125 |
| VAT area (cm2)* | 169.0 (145.0–213.0) | 167.5 (138.5–210.5) | 3.4 (− 2.6–18.6) | .130 |
| FMI* | 6.6 (5.2—8.9) | 7.5 (6.0–9.6) | 10.0 (5.5–22.3) | < .001 |
Normally distributed variables are presented as mean and SD, not normally distributed variables(*) are presented as median and interquartile range (IQR) and comparisons were performed by one sample t-test on percent variation (test val. = 0) or sign test, for normally or non-normally distributed variables, respectively
BMI body mass index, TOT total, VAT visceral adipose tissue, FMI fat mass index