FIGURE 3.

Visual predictive check (VPC) plots for the plasma tigecycline concentration. The Y-axis is the logarithm of the concentration. The open circles represent the observed concentrations. The solid red line represents the median of the observations. The solid blue lines represent the 5th and 95th percentiles of the observations. The blue shaded areas represent the 95% confidence intervals for the 5th and 95th percentiles, and the red shaded areas represent the medians of the predicted data.