Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Correlation of individual ELISA titers with survival after vaccination with purified peak 1 BoNT/A(Hc)
| Individual ELISA titera | Survival (no. alive/total)b | % Survival |
|---|---|---|
| ≤100 | 6/42 | 14.3 |
| 400 | 17/25 | 68.0 |
| ≥1,600 | 82/83 | 98.8 |
Serum was bled from each mouse individually. Titer is the reciprocal of the highest dilution having an A405 of greater than 0.2 after correction for background.
Mice were challenged with 100,000 i.p. LD50 of BoNT/A 21 days after the last vaccination.
