. 2024 Jan 29;15:1334308. doi: 10.3389/fpsyg.2024.1334308

Table 2.

Factors associated with anxiety (n: 58) in early IBD.

		Univariate analysis			Multivariate analysis
	HADS-Anxiety >7/total n anxiety/n total (%)	OR	95% confidence interval	p	Adjusted OR	95% confidence interval	p
Sex
Women	38/69 (55.1)	4.1	2.1–8.2	<0.001	4.85	2.21–10.6	<0.001
Men	20/87 (23.0)	1	2.1–8.2	<0.001	4.85	2.21–10.6	<0.001
Disease type
CD	39/80 (48.8)	2.85	1.45–5.63	0.002	3.5	1.54–8.2	0.003
UC	19/76 (25.0)	1	1.45–5.63	0.002	3.5	1.54–8.2	0.003
Current smoker
Yes	15/27 (55.6)	2.5	1.08–5.81	0.030	1.99	0.71–5.61	0.190
No	43/129 (33.3)	1	1.08–5.81	0.030	1.99	0.71–5.61	0.190
Use of biologics
Yes	7/37 (18.9)	0.31	0.13–0.76	0.009	0.139	0.04–0.40	<0.001
No	51/119 (42.9)	1	0.13–0.76	0.009	0.139	0.04–0.40	<0.001
SRRS ≥ 150
Yes	51/120 (42.5)	3.06	1.24–7.54	0.012	1.9	0.698–5.19	0.208
No	7/36 (19.4)	1	1.24–7.54	0.012	1.9	0.698–5.19	0.208

Only variables significantly related with anxiety in the univariate analysis are included in this table. CD, Crohn’s disease; UC, Ulcerative colitis; IBD, Inflammatory bowel disease; HADS, Hospital anxiety and depression scale; and SRRS, Social Readjustment Rating Scale. Bold values indicate statistical significance at the p < 0.05 level.