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. 2024 Jan 29;15:1334308. doi: 10.3389/fpsyg.2024.1334308

Table 4.

Factors associated with poor quality of life (n: 47) in early IBD.

Univariate analysis Multivariate analysis
IBDQ32 < 160/total n low IBDQ/n total (%) OR 95% confidence interval p Adjusted OR 95% confidence interval p
Sex
Women 30/69 (43.5) 3.17 1.55–6.46 0.001 3.04 1.39–6.53 0.005
Men 17/87 (19.5) 1
Disease type
CD 34/80 (42.5) 3.58 1.7–7.5 0.001 1.64 0.6–4.49 0.332
UC 13/76 (17.1) 1
BMI
<25 33/88 (37.5) 1 0.2–0.89 0.022 0.7 0.31–1.59 0.402
≥25 14/68 (20.6) 0.43
Use of mesalazine
Yes 25/110 (22.7) 0.321 0.15–0.67 0.002 0.51 0.19–1.4 0.194
No 22/46 (47.8) 0.321
Use of steroids
Yes 38/104 (36.5) 2.75 1.2–6.25 0.014 1.76 0.69–4.46 0.230
No 9/52 (17.3) 1
SRRS ≥ 150
Yes 43/120 (35.8) 4.47 1.48–13.48 0.005 3.55 1.08–11.6 0.036
No 4/36 (11.1) 1

Only variables significantly related with impairment in quality of life in the univariate analysis are included in this table. CD, Crohn’s disease; UC, Ulcerative colitis; BMI, Body mass index; IBDQ, Quality of life questionary for IBD; and SRRS, Social readjustment rating scale. Bold values indicate statistical significance at the p < 0.05 level.