TABLE 4.

Treatment‐related adverse events.

Adverse event, n (%)	Low‐dose group (n = 34)		Low‐dose group (n = 41)
	Grades 1–2	Grade 3	Grade 4	Grades 1–2	Grade 3	Grade 4
Total AEs	9 (26.4)	0	0	13 (31.7)	2 (4.9)	2 (4.9)
Hypertension	6 (17.6)	0	0	7 (17.1)	1 (2.4)	0
Diarrhea	1 (2.9)	0	0	2 (4.9)	0	0
Hemorrhage	1 (2.9)	0	0	2 (4.9)	0	1 (2.4)
Epilepsy	0	0	0	0	0	1 (2.4)
Fatigue	0	0	0	1 (2.4)	0	0
Oral ulcerations	1 (2.9)	0	0	1 (2.4)	0	0
Venous thrombosis	0	0	0	0	1 (2.4)	0