TABLE 1.
Characteristics of Japanese patients with solid tumors who underwent 324‐gene somatic genomic profiling test (FoundationOne CDx) or 324‐gene cell‐free DNA‐based comprehensive genomic profiling assay (FoundationOne Liquid CDx)
| FoundationOne CDx | FoundationOne Liquid CDx | Total | ||
|---|---|---|---|---|
| Patients, n | 3094 | 644 | 3738 | |
| Sex, n (%) | ||||
| Female | 1611 | 272 | 1883 | |
| Male | 1483 | 372 | 1855 | |
| Cancer type | ||||
| BRCA‐associated cancer | Breast | 196 | 72 | 268 |
| Ovary/fallopian tube/peritoneal | 253 | 21 | 274 | |
| Pancreas | 263 | 114 | 377 | |
| Prostate | 254 | 147 | 401 | |
| Total | 966 | 354 | 1320 | |
| Non‐BRCA‐associated cancer | Colorectal | 539 | 72 | 611 |
| Biliary | 229 | 55 | 284 | |
| Central nervous system | 152 | 2 | 154 | |
| Sarcoma | 138 | 12 | 150 | |
| Uterus | 115 | 3 | 118 | |
| Uterine cervix | 114 | 10 | 124 | |
| NSCLC | 105 | 35 | 140 | |
| Head and neck | 99 | 12 | 111 | |
| Stomach | 85 | 15 | 100 | |
| Thyroid | 78 | 4 | 82 | |
| Skin | 75 | 1 | 76 | |
| Unknown primary | 66 | 13 | 79 | |
| Esophagus | 63 | 10 | 73 | |
| Urinary | 63 | 8 | 71 | |
| Kidney | 23 | 6 | 29 | |
| Thymus | 14 | 2 | 16 | |
| Adrenal gland | 11 | 1 | 12 | |
| Duodenum | 11 | 2 | 13 | |
| SCLC | 11 | 2 | 13 | |
| Neuroendocrine carcinoma | 9 | 2 | 11 | |
| GIST | 8 | 2 | 10 | |
| Neuroendocrine tumor | 8 | 0 | 8 | |
| Mesothelioma | 7 | 0 | 7 | |
| Liver | 6 | 3 | 9 | |
| Soft tissue | 6 | 3 | 9 | |
| Vagina | 4 | 0 | 4 | |
| Testis | 2 | 1 | 3 | |
| Others | 87 | 14 | 101 | |
| Total | 2128 | 290 | 2418 | |
Abbreviations: GIST, gastrointestinal stromal tumor; NSCLC, non‐small‐cell lung cancer; SCLC, small‐cell lung cancer.