TABLE 3.

Risk of developing IBD in individuals with EoE compared to siblings.

Outcome IBD	Reference individuals	EoE
N total	2054	1209
N events	11	12
IR [95% CI]	0.81 [0.41–1.46]	1.52 [0.79–2.66]
IRD [95% CI]		0.71 [−0.28 to 1.69]
HR [95% CI]		2.19 [0.92–5.21]
aHR [95% CI]		2.48 [0.92–6.70]

Note: N/A values could not be calculated due to insufficient data.

Abbreviations: aHR, adjusted for age at EoE, sex, calendar year, county, education, and presence of autoimmune disease (see Table S2 for list of diseases); EoE, eosinophilic esophagitis; HR, crude hazard ratio; IBD, inflammatory bowel disease; IR, incidence rate; IRD, incidence rate difference.