TABLE 2.

Overview of genera associated with IBD.

Higher abundance in both CD and UC	Higher abundance only in CD	Higher abundance only in UC
(Clostridium) innocuum group (Eubacterium) brachy group (Ruminococcus) gnavus group Actinomyces Eggerthella Enterococcus Erysipelatoclostridium Faecalitalea Flavonifractor Gemella Haemophilus Intestinibacter Lactococcus Sellimonas Streptococcus Veillonella	(Eubacterium) fissicatena group Anaerotruncus Atopobium Candidatus Soleaferrea Dialister Dielma Eisenbergiella Fusobacterium Hungatella Lachnoclostridium Lachnospiraceae UCG‐010 Lactobacillus Megasphaera Mogibacterium Ruminococcaceae UBA1819 Solobacterium Tuzzerella Tyzzerella	Bifidobacterium Gordonibacter Lacticaseibacillus Ruminococcaceae DTU089 Turicibacter

Lower abundance in both CD and UC	Lower abundance only in CD	Lower abundance only in UC
(Eubacterium) ruminantium group (Eubacterium) siraeum group (Eubacterium) ventriosum group (Eubacterium) xylanophilum group Agathobacter Akkermansia Alistipes Barnesiella Christensenellaceae R‐7 group Coprococcus Fenollaria Fusicatenibacter Intestinimonas Lachnospira Lachnospiraceae CAG‐56 Lachnospiraceae ND3007 group Lachnospiraceae NK4A136 group Lachnospiraceae UCG‐001 Oscillospiraceae NK4A214 group Oscillospiraceae UCG‐002 Oscillospiraceae UCG‐003 Oscillospiraceae UCG‐005 Parabacteroides Paraprevotella Phascolarctobacterium Prevotella Roseburia Ruminococcaceae CAG‐352 Ruminococcus Subdoligranulum	(Eubacterium) eligens group (Eubacterium) hallii group Colidextribacter Collinsella Corynebacterium Faecalibacterium Holdemanella Lachnospiraceae FCS020 group Marvinbryantia Monoglobus Pseudomonas Romboutsia Turicibacter	Alloprevotella Angelakisella Bacteroides Bilophila Butyricimonas Coprobacter Desulfovibrio Family XIII UCG‐001 Lachnospiraceae AC2044 group Odoribacter Oxalobacter Prevotella_9 Victivallis

Note: All listed genera had an adjusted p‐value < 0.05 in all three statistical models and same direction of association. The genera are divided according to association with CD, UC or both CD and UC, and according to whether their abundance in IBD was higher or lower than in healthy individuals. They are named by genus name and sorted alphabetically. Further information is available in Table S6A and Figure S4. The names are colored based on whether the genus previously has been associated with IBD. Green: The same direction of association has been reported in literature. Orange: An opposite direction of association has been reported in literature. Black: The genus has not been associated with IBD previously.

Abbreviations: CD, Crohn's disease; IBD, inflammatory bowel diseases; UC, ulcerative colitis.