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. 2024 Jan 23;67(3):1662–1689. doi: 10.1021/acs.jmedchem.3c01979

Figure 9.

Figure 9

Crystal structure of SIRT3 in complex with carbaNAD (in green) and acetylated ACS2 peptide (in red). Pocket U is depicted in cyan, while pocket L is depicted in magenta with a surface style. F157 and E323 are residues in common with the two pockets and are depicted in orange (PDB 4FVT).