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(A) Compound 19d docked to 5-HT2AR, with predicted halogen bonding interaction (yellow dashes) with Phe2345.38. (B) Compound 19d docking pose overlaid with (R)-69 (pink) cryo-EM pose. (C) Compound 19d docked to 5-HT2BR. (D) Compound 19d 5-HT2BR docking pose overlaid with the LSD (yellow) cryo-EM pose. Blue dashes depict salt bridges and hydrogen bonds.
