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. 2024 Jan 19;15(2):302–309. doi: 10.1021/acsmedchemlett.3c00566

Scheme 1. Synthesis of Indazoles 6a6c.

Scheme 1

(a) LiOH, THF, H2O, rt; (b) dimethylamine hydrochloride or diethylamine, HATU, DIPEA, DMF, rt; (c) LiAlH4, or LiAlD4, THF, rt.