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. 2024 Feb 12;10(1):00547-2023. doi: 10.1183/23120541.00547-2023

FIGURE 2.

FIGURE 2

Cohen's d statistics for selected cardiac magnetic resonance imaging (cMRI), functional and other non-invasive variables at week 52 (safety set). Variables with no treatment effect are not included. #: determined from standard volumetric measurements; : log-transformed. n: number of patients with baseline and post-baseline measurements for a specific variable; Cohen's d statistics are reported below the n-values. For the standardised treatment effect sizes (STES): dark blue indicates a large change, mid-blue indicates a medium change and light blue indicates a small/fair change. The dotted lines at 0.20, 0.50 and 0.80 indicate the thresholds for a fair, medium or large change in STES, respectively. RV: right ventricular; RVSV: RV stroke volume; RVSVI: RVSV index; RVEDV: RV end-diastolic volume; RVESV: RV end-systolic volume; RVEF: RV ejection fraction; RVCO: RV cardiac output; RVCI: RV cardiac index; LV: left ventricular; LVSV: LV stroke volume; LVSVI: LVSV index; LVEDV: LV end-diastolic volume; LVESV: LV end-systolic volume; LVEF: LV ejection fraction; CO: cardiac output; CI: cardiac index; 6MWD: 6-min walk distance; NT-proBNP: N-terminal pro-brain natriuretic peptide; DBP: diastolic blood pressure; HR: heart rate.