Table 2.
Sensitivity analysis of the Mendelian randomization (MR) analysis results of DM2 and BMD
| Exposure | DM2 | |||||
|---|---|---|---|---|---|---|
| Outcome | TB-BMD | FN-BMD | UF-BMD | H-BMD | LS-BMD | |
| IVW (heterogeneity) | p value | 0.35 | 0.18 | 0.79 | 0.15 | 0.09 |
| Q | 253.22 | 92.52 | 166.64 | 1551.69 | 98.29 | |
| MR Egger (heterogeneity) | p value | 0.47 | 0.16 | 0.09 | 0.28 | 0.14 |
| Q | 252.81 | 92.48 | 166.51 | 1563.14 | 93.75 | |
| MR Egger (pleiotropy) | p value | 0.66 | 0.86 | 0.76 | 0.35 | 0.05 |
| intercept | 0.002 | 0.002 | 0.003 | 0.002 | 0.005 | |
Note: DM2 Type 2 Diabetes Mellitus, MR Mendelian randomization, TB Total body, FN, Femoral neck, UF, Ultradistal forearm, LS, Lumbar spine, BMD Bone mineral density, IVW inverse variance weighting, OR odds ratio, CI confidence interval